C-QT analysis dataset for quinidine with significant QTc effect (~50 ms prolongation)
cqtkit_data_quinidine.RdC-QT analysis dataset for quinidine with significant QTc effect (~50 ms prolongation)
Format
cqtkit_data_quinidine
A tibble: 643 × 15:
- ID
Uniuqe subject identifier
- TRTG
Treatment Group (Drug or Placebo)
- DOSE
numeric value of dose
- DOSEU
Units of DOSE
- DOSEF
Factor value of dose
- NTLD
Nominal time since last dose (h)
- CONC
Drug concentration
- CONCU
Drug concentration unit
- RR
RR after dose (ms)
- RRBL
Baseline RR beore dose (ms)
- HR
HR after dose (bpm)
- HRBL
Baseline HR beore dose (ms)
- HRBLM
Mean baseline HR across subjects (ms)
- deltaHRBL
Difference between baseline HR and mean baseline HR across subjects (ms)
- QT
QT after dose (ms)
- QTBL
Baseline QT before dose (ms)
- QTCB
Bazett's corrected QT after dose (ms)
- QTCBBL
Baseline Bazett's corrected QT before dose (ms)
- QTCBBLM
Mean baseline QTCB across subjects (ms)
- deltaQTCBBL
Difference between baseline QTCB and mean baseline QTCB across subjects (ms)
- QTCF
Fridericia's corrected QT after dose (ms)
- QTCFBL
Baseline Fridericia's corrected QT before dose(ms)
- QTCFBLM
Mean baseline QTCF across subjects (ms)
- deltaQTCFBL
Difference between baseline QTCF and mean baseline QTCF across subjects (ms)